WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for the enriched GO category are listed in this table. For each GO category, the first row lists its sub-root (biological process, molecular function, or cellular component), category name, and corresponding GO ID.
The second row lists the following statistics:
Finally, genes in the category are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:biological process       Name:response to stimulus       ID:GO:0050896
C=6636; O=23; E=11.79; R=1.95; rawP=5.88e-06; adjP=0.0025
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669
2  ENSG00000089159 NA PXN paxillin 5829 ENSG00000089159
3  ENSG00000173269 NA MMRN2 multimerin 2 79812 ENSG00000173269
4  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
5  ENSG00000001617 NA SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 6405 ENSG00000001617
6  ENSG00000104998 NA IL27RA interleukin 27 receptor, alpha 9466 ENSG00000104998
7  ENSG00000172716 NA SLFN11 schlafen family member 11 91607 ENSG00000172716
8  ENSG00000178695 NA KCTD12 potassium channel tetramerisation domain containing 12 115207 ENSG00000178695
9  ENSG00000104689 NA TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 8797 ENSG00000104689
10  ENSG00000127533 NA F2RL3 coagulation factor II (thrombin) receptor-like 3 9002 ENSG00000127533
11  ENSG00000105538 NA RASIP1 Ras interacting protein 1 54922 ENSG00000105538
12  ENSG00000175040 NA CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 9435 ENSG00000175040
13  ENSG00000149564 NA ESAM endothelial cell adhesion molecule 90952 ENSG00000149564
14  ENSG00000163083 NA INHBB inhibin, beta B 3625 ENSG00000163083
15  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
16  ENSG00000224982 NA TMEM233 transmembrane protein 233 387890 ENSG00000224982
17  ENSG00000120278 NA PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 57480 ENSG00000120278
18  ENSG00000184937 NA WT1 Wilms tumor 1 7490 ENSG00000184937
19  ENSG00000196411 NA EPHB4 EPH receptor B4 2050 ENSG00000196411
20  ENSG00000100276 NA RASL10A RAS-like, family 10, member A 10633 ENSG00000100276
21  ENSG00000159167 NA STC1 stanniocalcin 1 6781 ENSG00000159167
22  ENSG00000136237 NA RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 9771 ENSG00000136237
23  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867


Database:biological process       Name:single-organism process       ID:GO:0044699
C=7682; O=23; E=13.65; R=1.68; rawP=0.0001; adjP=0.0061
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000113758 NA DBN1 drebrin 1 1627 ENSG00000113758
2  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669
3  ENSG00000089159 NA PXN paxillin 5829 ENSG00000089159
4  ENSG00000173269 NA MMRN2 multimerin 2 79812 ENSG00000173269
5  ENSG00000121039 NA RDH10 retinol dehydrogenase 10 (all-trans) 157506 ENSG00000121039
6  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
7  ENSG00000001617 NA SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 6405 ENSG00000001617
8  ENSG00000104689 NA TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 8797 ENSG00000104689
9  ENSG00000104998 NA IL27RA interleukin 27 receptor, alpha 9466 ENSG00000104998
10  ENSG00000178695 NA KCTD12 potassium channel tetramerisation domain containing 12 115207 ENSG00000178695
11  ENSG00000127533 NA F2RL3 coagulation factor II (thrombin) receptor-like 3 9002 ENSG00000127533
12  ENSG00000105538 NA RASIP1 Ras interacting protein 1 54922 ENSG00000105538
13  ENSG00000175040 NA CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 9435 ENSG00000175040
14  ENSG00000149564 NA ESAM endothelial cell adhesion molecule 90952 ENSG00000149564
15  ENSG00000163083 NA INHBB inhibin, beta B 3625 ENSG00000163083
16  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
17  ENSG00000120278 NA PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 57480 ENSG00000120278
18  ENSG00000184937 NA WT1 Wilms tumor 1 7490 ENSG00000184937
19  ENSG00000196411 NA EPHB4 EPH receptor B4 2050 ENSG00000196411
20  ENSG00000100276 NA RASL10A RAS-like, family 10, member A 10633 ENSG00000100276
21  ENSG00000159167 NA STC1 stanniocalcin 1 6781 ENSG00000159167
22  ENSG00000136237 NA RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 9771 ENSG00000136237
23  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867


Database:biological process       Name:blood vessel morphogenesis       ID:GO:0048514
C=433; O=6; E=0.77; R=7.80; rawP=9.03e-05; adjP=0.0061
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000184937 NA WT1 Wilms tumor 1 7490 ENSG00000184937
2  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
3  ENSG00000196411 NA EPHB4 EPH receptor B4 2050 ENSG00000196411
4  ENSG00000105538 NA RASIP1 Ras interacting protein 1 54922 ENSG00000105538
5  ENSG00000173269 NA MMRN2 multimerin 2 79812 ENSG00000173269
6  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867


Database:biological process       Name:single organism signaling       ID:GO:0044700
C=4646; O=18; E=8.26; R=2.18; rawP=9.64e-05; adjP=0.0061
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000113758 NA DBN1 drebrin 1 1627 ENSG00000113758
2  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669
3  ENSG00000089159 NA PXN paxillin 5829 ENSG00000089159
4  ENSG00000173269 NA MMRN2 multimerin 2 79812 ENSG00000173269
5  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
6  ENSG00000104998 NA IL27RA interleukin 27 receptor, alpha 9466 ENSG00000104998
7  ENSG00000178695 NA KCTD12 potassium channel tetramerisation domain containing 12 115207 ENSG00000178695
8  ENSG00000104689 NA TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 8797 ENSG00000104689
9  ENSG00000127533 NA F2RL3 coagulation factor II (thrombin) receptor-like 3 9002 ENSG00000127533
10  ENSG00000105538 NA RASIP1 Ras interacting protein 1 54922 ENSG00000105538
11  ENSG00000163083 NA INHBB inhibin, beta B 3625 ENSG00000163083
12  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
13  ENSG00000120278 NA PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 57480 ENSG00000120278
14  ENSG00000196411 NA EPHB4 EPH receptor B4 2050 ENSG00000196411
15  ENSG00000100276 NA RASL10A RAS-like, family 10, member A 10633 ENSG00000100276
16  ENSG00000136237 NA RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 9771 ENSG00000136237
17  ENSG00000159167 NA STC1 stanniocalcin 1 6781 ENSG00000159167
18  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867


Database:biological process       Name:cell communication       ID:GO:0007154
C=4770; O=18; E=8.48; R=2.12; rawP=0.0001; adjP=0.0061
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000113758 NA DBN1 drebrin 1 1627 ENSG00000113758
2  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669
3  ENSG00000089159 NA PXN paxillin 5829 ENSG00000089159
4  ENSG00000173269 NA MMRN2 multimerin 2 79812 ENSG00000173269
5  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
6  ENSG00000104998 NA IL27RA interleukin 27 receptor, alpha 9466 ENSG00000104998
7  ENSG00000178695 NA KCTD12 potassium channel tetramerisation domain containing 12 115207 ENSG00000178695
8  ENSG00000104689 NA TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 8797 ENSG00000104689
9  ENSG00000127533 NA F2RL3 coagulation factor II (thrombin) receptor-like 3 9002 ENSG00000127533
10  ENSG00000105538 NA RASIP1 Ras interacting protein 1 54922 ENSG00000105538
11  ENSG00000163083 NA INHBB inhibin, beta B 3625 ENSG00000163083
12  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
13  ENSG00000120278 NA PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 57480 ENSG00000120278
14  ENSG00000196411 NA EPHB4 EPH receptor B4 2050 ENSG00000196411
15  ENSG00000100276 NA RASL10A RAS-like, family 10, member A 10633 ENSG00000100276
16  ENSG00000136237 NA RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 9771 ENSG00000136237
17  ENSG00000159167 NA STC1 stanniocalcin 1 6781 ENSG00000159167
18  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867


Database:biological process       Name:signal transduction       ID:GO:0007165
C=4139; O=17; E=7.36; R=2.31; rawP=9.08e-05; adjP=0.0061
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669
2  ENSG00000089159 NA PXN paxillin 5829 ENSG00000089159
3  ENSG00000173269 NA MMRN2 multimerin 2 79812 ENSG00000173269
4  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
5  ENSG00000104998 NA IL27RA interleukin 27 receptor, alpha 9466 ENSG00000104998
6  ENSG00000178695 NA KCTD12 potassium channel tetramerisation domain containing 12 115207 ENSG00000178695
7  ENSG00000104689 NA TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 8797 ENSG00000104689
8  ENSG00000127533 NA F2RL3 coagulation factor II (thrombin) receptor-like 3 9002 ENSG00000127533
9  ENSG00000105538 NA RASIP1 Ras interacting protein 1 54922 ENSG00000105538
10  ENSG00000163083 NA INHBB inhibin, beta B 3625 ENSG00000163083
11  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
12  ENSG00000120278 NA PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 57480 ENSG00000120278
13  ENSG00000196411 NA EPHB4 EPH receptor B4 2050 ENSG00000196411
14  ENSG00000100276 NA RASL10A RAS-like, family 10, member A 10633 ENSG00000100276
15  ENSG00000136237 NA RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 9771 ENSG00000136237
16  ENSG00000159167 NA STC1 stanniocalcin 1 6781 ENSG00000159167
17  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867


Database:biological process       Name:signaling       ID:GO:0023052
C=4646; O=18; E=8.26; R=2.18; rawP=9.64e-05; adjP=0.0061
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000113758 NA DBN1 drebrin 1 1627 ENSG00000113758
2  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669
3  ENSG00000089159 NA PXN paxillin 5829 ENSG00000089159
4  ENSG00000173269 NA MMRN2 multimerin 2 79812 ENSG00000173269
5  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
6  ENSG00000104998 NA IL27RA interleukin 27 receptor, alpha 9466 ENSG00000104998
7  ENSG00000178695 NA KCTD12 potassium channel tetramerisation domain containing 12 115207 ENSG00000178695
8  ENSG00000104689 NA TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 8797 ENSG00000104689
9  ENSG00000127533 NA F2RL3 coagulation factor II (thrombin) receptor-like 3 9002 ENSG00000127533
10  ENSG00000105538 NA RASIP1 Ras interacting protein 1 54922 ENSG00000105538
11  ENSG00000163083 NA INHBB inhibin, beta B 3625 ENSG00000163083
12  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
13  ENSG00000120278 NA PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 57480 ENSG00000120278
14  ENSG00000196411 NA EPHB4 EPH receptor B4 2050 ENSG00000196411
15  ENSG00000100276 NA RASL10A RAS-like, family 10, member A 10633 ENSG00000100276
16  ENSG00000136237 NA RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 9771 ENSG00000136237
17  ENSG00000159167 NA STC1 stanniocalcin 1 6781 ENSG00000159167
18  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867


Database:biological process       Name:blood vessel development       ID:GO:0001568
C=492; O=6; E=0.87; R=6.86; rawP=0.0002; adjP=0.0071
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000184937 NA WT1 Wilms tumor 1 7490 ENSG00000184937
2  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
3  ENSG00000196411 NA EPHB4 EPH receptor B4 2050 ENSG00000196411
4  ENSG00000105538 NA RASIP1 Ras interacting protein 1 54922 ENSG00000105538
5  ENSG00000173269 NA MMRN2 multimerin 2 79812 ENSG00000173269
6  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867


Database:biological process       Name:regulation of vasculature development       ID:GO:1901342
C=166; O=4; E=0.30; R=13.56; rawP=0.0002; adjP=0.0071
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000184937 NA WT1 Wilms tumor 1 7490 ENSG00000184937
2  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
3  ENSG00000173269 NA MMRN2 multimerin 2 79812 ENSG00000173269
4  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867


Database:biological process       Name:regulation of cGMP biosynthetic process       ID:GO:0030826
C=11; O=2; E=0.02; R=102.31; rawP=0.0002; adjP=0.0071
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
2  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867


Database:molecular function       Name:guanyl-nucleotide exchange factor activity       ID:GO:0005085
C=183; O=4; E=0.29; R=13.92; rawP=0.0002; adjP=0.0116
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669
2  ENSG00000136237 NA RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 9771 ENSG00000136237
3  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
4  ENSG00000120278 NA PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 57480 ENSG00000120278


Database:molecular function       Name:GTPase regulator activity       ID:GO:0030695
C=446; O=4; E=0.70; R=5.71; rawP=0.0048; adjP=0.0770
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669
2  ENSG00000136237 NA RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 9771 ENSG00000136237
3  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
4  ENSG00000120278 NA PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 57480 ENSG00000120278


Database:molecular function       Name:peptide receptor activity       ID:GO:0001653
C=118; O=2; E=0.19; R=10.79; rawP=0.0146; adjP=0.0770
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
2  ENSG00000127533 NA F2RL3 coagulation factor II (thrombin) receptor-like 3 9002 ENSG00000127533


Database:molecular function       Name:transmembrane signaling receptor activity       ID:GO:0004888
C=1231; O=6; E=1.93; R=3.10; rawP=0.0103; adjP=0.0770
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
2  ENSG00000104689 NA TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 8797 ENSG00000104689
3  ENSG00000104998 NA IL27RA interleukin 27 receptor, alpha 9466 ENSG00000104998
4  ENSG00000196411 NA EPHB4 EPH receptor B4 2050 ENSG00000196411
5  ENSG00000127533 NA F2RL3 coagulation factor II (thrombin) receptor-like 3 9002 ENSG00000127533
6  ENSG00000182162 NA P2RY8 purinergic receptor P2Y, G-protein coupled, 8 286530 ENSG00000182162


Database:molecular function       Name:small GTPase regulator activity       ID:GO:0005083
C=299; O=3; E=0.47; R=6.39; rawP=0.0111; adjP=0.0770
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669
2  ENSG00000136237 NA RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 9771 ENSG00000136237
3  ENSG00000120278 NA PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 57480 ENSG00000120278


Database:molecular function       Name:signaling receptor activity       ID:GO:0038023
C=1325; O=6; E=2.08; R=2.88; rawP=0.0145; adjP=0.0770
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
2  ENSG00000104689 NA TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 8797 ENSG00000104689
3  ENSG00000104998 NA IL27RA interleukin 27 receptor, alpha 9466 ENSG00000104998
4  ENSG00000196411 NA EPHB4 EPH receptor B4 2050 ENSG00000196411
5  ENSG00000127533 NA F2RL3 coagulation factor II (thrombin) receptor-like 3 9002 ENSG00000127533
6  ENSG00000182162 NA P2RY8 purinergic receptor P2Y, G-protein coupled, 8 286530 ENSG00000182162


Database:molecular function       Name:hormone activity       ID:GO:0005179
C=111; O=2; E=0.17; R=11.47; rawP=0.0130; adjP=0.0770
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163083 NA INHBB inhibin, beta B 3625 ENSG00000163083
2  ENSG00000159167 NA STC1 stanniocalcin 1 6781 ENSG00000159167


Database:molecular function       Name:receptor activity       ID:GO:0004872
C=1531; O=7; E=2.40; R=2.91; rawP=0.0075; adjP=0.0770
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
2  ENSG00000001617 NA SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 6405 ENSG00000001617
3  ENSG00000104689 NA TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 8797 ENSG00000104689
4  ENSG00000104998 NA IL27RA interleukin 27 receptor, alpha 9466 ENSG00000104998
5  ENSG00000196411 NA EPHB4 EPH receptor B4 2050 ENSG00000196411
6  ENSG00000127533 NA F2RL3 coagulation factor II (thrombin) receptor-like 3 9002 ENSG00000127533
7  ENSG00000182162 NA P2RY8 purinergic receptor P2Y, G-protein coupled, 8 286530 ENSG00000182162


Database:molecular function       Name:nucleoside-triphosphatase regulator activity       ID:GO:0060589
C=458; O=4; E=0.72; R=5.56; rawP=0.0053; adjP=0.0770
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669
2  ENSG00000136237 NA RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 9771 ENSG00000136237
3  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
4  ENSG00000120278 NA PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 57480 ENSG00000120278


Database:molecular function       Name:Ras guanyl-nucleotide exchange factor activity       ID:GO:0005088
C=112; O=2; E=0.18; R=11.37; rawP=0.0132; adjP=0.0770
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000136237 NA RAPGEF5 Rap guanine nucleotide exchange factor (GEF) 5 9771 ENSG00000136237
2  ENSG00000120278 NA PLEKHG1 pleckstrin homology domain containing, family G (with RhoGef domain) member 1 57480 ENSG00000120278


Database:cellular component       Name:plasma membrane       ID:GO:0005886
C=4289; O=13; E=7.04; R=1.85; rawP=0.0118; adjP=0.1280
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000149564 NA ESAM endothelial cell adhesion molecule 90952 ENSG00000149564
2  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669
3  ENSG00000089159 NA PXN paxillin 5829 ENSG00000089159
4  ENSG00000182162 NA P2RY8 purinergic receptor P2Y, G-protein coupled, 8 286530 ENSG00000182162
5  ENSG00000174951 NA FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2523 ENSG00000174951
6  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
7  ENSG00000104998 NA IL27RA interleukin 27 receptor, alpha 9466 ENSG00000104998
8  ENSG00000178695 NA KCTD12 potassium channel tetramerisation domain containing 12 115207 ENSG00000178695
9  ENSG00000196411 NA EPHB4 EPH receptor B4 2050 ENSG00000196411
10  ENSG00000127533 NA F2RL3 coagulation factor II (thrombin) receptor-like 3 9002 ENSG00000127533
11  ENSG00000100276 NA RASL10A RAS-like, family 10, member A 10633 ENSG00000100276
12  ENSG00000159167 NA STC1 stanniocalcin 1 6781 ENSG00000159167
13  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867


Database:cellular component       Name:occluding junction       ID:GO:0070160
C=97; O=2; E=0.16; R=12.56; rawP=0.0110; adjP=0.1280
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000149564 NA ESAM endothelial cell adhesion molecule 90952 ENSG00000149564
2  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669


Database:cellular component       Name:tight junction       ID:GO:0005923
C=97; O=2; E=0.16; R=12.56; rawP=0.0110; adjP=0.1280
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000149564 NA ESAM endothelial cell adhesion molecule 90952 ENSG00000149564
2  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669


Database:cellular component       Name:apical junction complex       ID:GO:0043296
C=113; O=2; E=0.19; R=10.78; rawP=0.0147; adjP=0.1280
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000149564 NA ESAM endothelial cell adhesion molecule 90952 ENSG00000149564
2  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669


Database:cellular component       Name:membrane       ID:GO:0016020
C=7811; O=19; E=12.83; R=1.48; rawP=0.0155; adjP=0.1280
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669
2  ENSG00000089159 NA PXN paxillin 5829 ENSG00000089159
3  ENSG00000182162 NA P2RY8 purinergic receptor P2Y, G-protein coupled, 8 286530 ENSG00000182162
4  ENSG00000121039 NA RDH10 retinol dehydrogenase 10 (all-trans) 157506 ENSG00000121039
5  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
6  ENSG00000001617 NA SEMA3F sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F 6405 ENSG00000001617
7  ENSG00000104998 NA IL27RA interleukin 27 receptor, alpha 9466 ENSG00000104998
8  ENSG00000178695 NA KCTD12 potassium channel tetramerisation domain containing 12 115207 ENSG00000178695
9  ENSG00000104689 NA TNFRSF10A tumor necrosis factor receptor superfamily, member 10a 8797 ENSG00000104689
10  ENSG00000127533 NA F2RL3 coagulation factor II (thrombin) receptor-like 3 9002 ENSG00000127533
11  ENSG00000175040 NA CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 9435 ENSG00000175040
12  ENSG00000149564 NA ESAM endothelial cell adhesion molecule 90952 ENSG00000149564
13  ENSG00000224982 NA TMEM233 transmembrane protein 233 387890 ENSG00000224982
14  ENSG00000095370 NA SH2D3C SH2 domain containing 3C 10044 ENSG00000095370
15  ENSG00000174951 NA FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2523 ENSG00000174951
16  ENSG00000196411 NA EPHB4 EPH receptor B4 2050 ENSG00000196411
17  ENSG00000100276 NA RASL10A RAS-like, family 10, member A 10633 ENSG00000100276
18  ENSG00000159167 NA STC1 stanniocalcin 1 6781 ENSG00000159167
19  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867


Database:cellular component       Name:Golgi stack       ID:GO:0005795
C=118; O=2; E=0.19; R=10.32; rawP=0.0160; adjP=0.1280
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000105538 NA RASIP1 Ras interacting protein 1 54922 ENSG00000105538
2  ENSG00000174951 NA FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2523 ENSG00000174951


Database:cellular component       Name:cell periphery       ID:GO:0071944
C=4377; O=13; E=7.19; R=1.81; rawP=0.0140; adjP=0.1280
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000149564 NA ESAM endothelial cell adhesion molecule 90952 ENSG00000149564
2  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669
3  ENSG00000089159 NA PXN paxillin 5829 ENSG00000089159
4  ENSG00000182162 NA P2RY8 purinergic receptor P2Y, G-protein coupled, 8 286530 ENSG00000182162
5  ENSG00000174951 NA FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2523 ENSG00000174951
6  ENSG00000169418 NA NPR1 natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A) 4881 ENSG00000169418
7  ENSG00000104998 NA IL27RA interleukin 27 receptor, alpha 9466 ENSG00000104998
8  ENSG00000178695 NA KCTD12 potassium channel tetramerisation domain containing 12 115207 ENSG00000178695
9  ENSG00000196411 NA EPHB4 EPH receptor B4 2050 ENSG00000196411
10  ENSG00000127533 NA F2RL3 coagulation factor II (thrombin) receptor-like 3 9002 ENSG00000127533
11  ENSG00000100276 NA RASL10A RAS-like, family 10, member A 10633 ENSG00000100276
12  ENSG00000159167 NA STC1 stanniocalcin 1 6781 ENSG00000159167
13  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867


Database:cellular component       Name:trans-Golgi network       ID:GO:0005802
C=128; O=2; E=0.21; R=9.52; rawP=0.0186; adjP=0.1302
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669
2  ENSG00000175040 NA CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 9435 ENSG00000175040


Database:cellular component       Name:Golgi apparatus part       ID:GO:0044431
C=672; O=4; E=1.10; R=3.63; rawP=0.0231; adjP=0.1437
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000105538 NA RASIP1 Ras interacting protein 1 54922 ENSG00000105538
2  ENSG00000175040 NA CHST2 carbohydrate (N-acetylglucosamine-6-O) sulfotransferase 2 9435 ENSG00000175040
3  ENSG00000164867 NA NOS3 nitric oxide synthase 3 (endothelial cell) 4846 ENSG00000164867
4  ENSG00000174951 NA FUT1 fucosyltransferase 1 (galactoside 2-alpha-L-fucosyltransferase, H blood group) 2523 ENSG00000174951


Database:cellular component       Name:cell junction       ID:GO:0030054
C=737; O=4; E=1.21; R=3.31; rawP=0.0311; adjP=0.1624
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000149564 NA ESAM endothelial cell adhesion molecule 90952 ENSG00000149564
2  ENSG00000178695 NA KCTD12 potassium channel tetramerisation domain containing 12 115207 ENSG00000178695
3  ENSG00000108669 NA CYTH1 cytohesin 1 9267 ENSG00000108669
4  ENSG00000089159 NA PXN paxillin 5829 ENSG00000089159




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).